与强直性脊柱炎密切相关的HLA分子是

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HLA-B7 HLA-B27 HLA-DR4 HLA-B25 HLA-DR3

强直性脊柱炎常为多发强直性脊柱炎发展常为对称性，并逐渐向上蔓延强直性脊柱炎不发生化脓强直性脊柱炎和结核都可出现死骨骶髂关节结核HLA-B₂₇阴性

HLA-DR9 HLA-DR4 HLA-B27 HLA-DR2 HLA-DR5

抗核抗体阳性见于多数患者 HLA-DR4阳性提示预后差 HLA-B27阴性的患者肯定不是强直性脊柱炎 HLA-B27阳性提示强直性脊柱炎的可能性大 HLA-B27阴性预后差

HLA-A5 HLA-B5 HLA-B7 HLA-B27 HLA-DR3

抗核抗体阳性见于多数患者 HLA-DR4阳性提示预后差 HLA-1327阴性的患者肯定不是强直性脊柱炎 HLA-]327阳性提示强直性脊柱炎的可能性大 HLA-B27阴性预后差

HLA－DR4 HLA－B7 HLA－B5 HLA－B27 HLA－DR

强直性脊柱炎常为多发强直性脊柱炎发展常为对称性，并逐渐向上蔓延强直性脊柱炎不发生化脓强直性脊柱炎和结核都可出现死骨骶髂关节结核HLA-B₂₇，阴性

HLA-DR3 HLA-DR4 HLA-B27 HLA-DR9 HLA-DR5

HLA-5 HLA-B7 HLA-B8 HLA-B27

HLA-B8 HLA-DR3 HLA-B27 HLA-B7 HLA-A5

强直性脊柱炎常为多发强直性脊柱炎发展常为对称性，并逐渐向上蔓延强直性脊柱炎不发生化脓强直性脊柱炎和结核都可出现死骨骶髂关节结核HLA-B27阴性

HLA-A5 HLA-B7 HLA-B8 HLA-B27 HL A-DR3

HLA-DR4 HLA-B27 HLA-DR9 HLA-DR2 HLA-DR5