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Ohchildhowyouastonishedme—Ithoughtyouwereinthegarden.
Thewholeideatobuildadeluxehotelheresounds{{U}}insane{{/U}}tome.
ThenumberoftheUnitesStatescitizenswhoareeligibletovotecontinuestoincrease.
Thetownisfamousforitsmagnificentchurchtowers.
Itissaidthatthehousesalongthisstreetwillsoonbe{{U}}demolished{{/U}}.
UnitedNations AmajorsegmentoftheUntiedNationsistheGeneralAssemblywhichconsistsofrepresentativesfromallgovernmentsthathaveratifiedtheUNCharter.Asof1995185stateshadmembershipinthegeneralAssembly.AdditionallytheVaticanSwitzerlandandthePalestineLiberationOrganizationhavenonvotingobserverstatusintheGeneralAssembly.TheGeneralAssemblyapprovestheUN’’sbudgetactswiththeSecurityCounciltoselecttheSecretary-generalandjudgesoftheInternationalCourtofJusticeandpassesresolutionsonissuesrangingfromself-determinationandcolonialismtowomen’’srightsandtheglobaldistributionofwealth. TheGeneralAssemblycanmeetandvoteonanysubjectunlesstheSecurityCouncilisdealingwithitoratleastpretendingto.Howeveritsdecisionsonlycarrymoralforce—unliketheCouncil’’s.They’’renotbindingininternationallaws.ButtheAssemblyvotesareanimportantopinionpollonhowandwhatthemajorityoftheworldthinksaboutissues.Importantquestionsneedatwo-thirdsvoteoftheAssemblytopass. Thequestionofwhatisanimportantquestionisn’’timportant.Itsdecidedbythedelegatesthemselves—byasimplemajority. AlthoughtheGeneralAssemblyhasnotrecognizedauthoritytoenforceitsconclusionsonanythingotherthaninternalUNmattersitmakesitsviewpointsonissuesthatarebroughtbeforeitisknowninoneofthethreeways.AGeneralAssemblydeclarationisabroadstatementofgeneralprinciplesuchastheUniversalDeclarationofHumanRightspassedin1948.Declarationsareoftenputforwardasanexpressionofanidealinpracticetheyareregularlyignored.AGeneralAssemblyresolutionisessentiallyadocumentthatrecommendsthatmemberstatestakeaparticularpolicyaction.StatesclaimsovereigntyandmaketheirowndecisionsastowhethertheywillfollowaGeneralAssemblyresolution.Insomecaseshoweverifmanystatesimplementaparticularresolutionotherstatesthatmaynotwishtoactontheresolutionmayfeelthemselvespressuredtodosoanyway.Attheveryleastaresolutionhastheeffectoflegitimizingthepoliciesofthosestatesthatwishtocomplywiththeresolution.FinallyaGeneralAssemblyconventionortreatyhastwomeanings.ThemorecomprehensiveconventionreferstomultilateraltreatiesvotedonbytheGeneralAssemblythatuponpassagebytheGeneralAssemblyarecarriedbacktothecapitalsofmemberstatesforratificationbywhatevermeanseachstateusesdomestically.InothercasesaGeneralAssemblyconventionrefersspecificallytoatreatysignedbetweentheUnitedNationsandthegovernmentofanation-stateaswhenin1956EgyptagreedtoallowUnitedNationspeacekeepingforcestoenterEgyptianterritory. TheGeneralAssemblyisresponsiblefordealingwiththeinternationalmatters.
Thedoctorsoonmadetheworriedpatientfeelcomfortable.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
UnitedNations AmajorsegmentoftheUntiedNationsistheGeneralAssemblywhichconsistsofrepresentativesfromallgovernmentsthathaveratifiedtheUNCharter.Asof1995185stateshadmembershipinthegeneralAssembly.AdditionallytheVaticanSwitzerlandandthePalestineLiberationOrganizationhavenonvotingobserverstatusintheGeneralAssembly.TheGeneralAssemblyapprovestheUN’’sbudgetactswiththeSecurityCounciltoselecttheSecretary-generalandjudgesoftheInternationalCourtofJusticeandpassesresolutionsonissuesrangingfromself-determinationandcolonialismtowomen’’srightsandtheglobaldistributionofwealth. TheGeneralAssemblycanmeetandvoteonanysubjectunlesstheSecurityCouncilisdealingwithitoratleastpretendingto.Howeveritsdecisionsonlycarrymoralforce—unliketheCouncil’’s.They’’renotbindingininternationallaws.ButtheAssemblyvotesareanimportantopinionpollonhowandwhatthemajorityoftheworldthinksaboutissues.Importantquestionsneedatwo-thirdsvoteoftheAssemblytopass. Thequestionofwhatisanimportantquestionisn’’timportant.Itsdecidedbythedelegatesthemselves—byasimplemajority. AlthoughtheGeneralAssemblyhasnotrecognizedauthoritytoenforceitsconclusionsonanythingotherthaninternalUNmattersitmakesitsviewpointsonissuesthatarebroughtbeforeitisknowninoneofthethreeways.AGeneralAssemblydeclarationisabroadstatementofgeneralprinciplesuchastheUniversalDeclarationofHumanRightspassedin1948.Declarationsareoftenputforwardasanexpressionofanidealinpracticetheyareregularlyignored.AGeneralAssemblyresolutionisessentiallyadocumentthatrecommendsthatmemberstatestakeaparticularpolicyaction.StatesclaimsovereigntyandmaketheirowndecisionsastowhethertheywillfollowaGeneralAssemblyresolution.Insomecaseshoweverifmanystatesimplementaparticularresolutionotherstatesthatmaynotwishtoactontheresolutionmayfeelthemselvespressuredtodosoanyway.Attheveryleastaresolutionhastheeffectoflegitimizingthepoliciesofthosestatesthatwishtocomplywiththeresolution.FinallyaGeneralAssemblyconventionortreatyhastwomeanings.ThemorecomprehensiveconventionreferstomultilateraltreatiesvotedonbytheGeneralAssemblythatuponpassagebytheGeneralAssemblyarecarriedbacktothecapitalsofmemberstatesforratificationbywhatevermeanseachstateusesdomestically.InothercasesaGeneralAssemblyconventionrefersspecificallytoatreatysignedbetweentheUnitedNationsandthegovernmentofanation-stateaswhenin1956EgyptagreedtoallowUnitedNationspeacekeepingforcestoenterEgyptianterritory. TheGeneralAssemblypressesitsmemberstatestoimplementitsresolution.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
Wecanutilizewaterforproducingelectricpower.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
Euthanasia:aHeatedlyDebatedTopic Wemustn’’tdelayanylonger...?swallowing吞咽isdifficult...andbreathingthat’’salsodifficult.Thosemusclesareweakeningtoo...wemustn’’tdelayanylonger. ThesewerethewordsofDutchman荷兰人CeesvanwendeldeJoodeaskinghisdoctortohelphimdie.AffectedwithaseriousdiseasevanVendelwasnolongerabletospeakclearlyandheknewtherewasnohopeofrecoveryandthathisconditionwasrapidlydeteriorating. VanVenderslastthreemonthsoflifebeforebeinggivenafinallethalinjectionbyhisdoctorwerefilmedandfirstshownontelevisionlastyearintheNetherlands.Theprogrammehassincebeenboughtby20countriesandeachtimeitisshownitstartsanationwidedebateonthesubject. TheNetherlandsistheonlycountryinEuropewhichpermitseuthanasia安乐死althoughitisnottechnicallylegalthere.HoweverdoctorswhocarryouteuthanasiaunderstrictguidelinesintroducedbytheDutchParliament议会twoyearsagoareusuallynotprosecuted.Theguidelinesdemandthatthepatientisexperiencingextremesufferingthatthereisnochanceofacureandthatthepatienthasmaderepeatedrequestsforeuthanasia.Inadditiontothisaseconddoctormustconfirm证实thatthesecriteriahavebeenmetandthedeathmustbereportedtothepolicedepartment. Shoulddoctorsbeallowedtotaketheliveofothers?Dr.WilfredVanOijenCeesvanVendel’’sdoctorexplainshowhelooksatthequestion: Wellit’’snotasifIinplanningtomurderacrowdofpeoplewithamachinegun.InthatcasekillingistheworstthingIcanimagine.Butthat’’sentirelydifferentfrommyworkasadoctor.IcareforpeopleandItrytoensurethattheydon’tsuffertoomuch.That’’sverydifferentthing. Manypeoplethougharetotallyagainstthepracticeofeuthanasia.Dr.AndrewFergusonChairmanoftheorganizationHealthcareopposedtoEuthanasiasaysthatinthevastmajorityofeuthanasiacaseswhatthepatientisactuallyaskingforissomethingelse.Theymaywantahealthprofessionaltoopenupcommunicationforthemwiththeirlovedonesorfamily—there’’snearlyalwaysanotherquestionbehindthequestion. Britainalsohasastrongtraditionofhospices—specialhospitalswhichcareonlyforthedyingandtheirspecialneeds.CicelySaundersPresidentoftheNationalHospiceCouncilandafoundermemberofthehospicemovementarguesthateuthanasiadoesn’’ttakeintoaccountthattherearewaysofcaringforthedying.Sheisalsoconcernedthatallowingeuthanasiawouldunderminetheneedforcareandconsiderationofawiderangeofpeople;It’’sveryeasyinsocietynowfortheelderlythedisabled伤残的andthedependenttofeelthattheyareburdensandthereforethattheyoughttoopt脱离out.Ithinkthatanythingthatlegallyallowstheshorteningoflifedoesmakethosepeoplemorevulnerable脆弱的. Manyfindthisprohibitionofanindividual’’srighttothepaternalistic家长式的.Althoughtheyagreethatlifeisimportantandshouldberespectedtheyfeelthatthequalityoflifeshouldnotbeignored.Dr.VanOijenbelievesthatpeoplehavethefundamentalrighttochooseforthemselvesiftheywanttodie:Whatthosepeoplewhoopposeeuthanasiaaretellingmeisthatdyingpeoplehaven’ttheright.Andthatwhenpeopleareveryillweareallafraidoftheirdeath.Buttherearesituationswheredeathisafriend.Andinthosecaseswhynot? Butwhynot?isaquestionwhichmightcausestrongemotion.ThefilmshowingCeesVanVendel’’sdeathwasbothmovingandsensitive.Hisdoctorwasclearlyafamilyfriend;hiswifehadonlyherhusband’’sinterestsatheart.Somehoweverwouldarguethatitwouldbedangeroustousethisparticularexampletosupportthecaseforeuthanasia.Notallpatientswouldreceivesuchahighlevelofindividualcareandattention. Whoisagainsteuthanasia?
OnAntibodies Substancesforeigntothebodysuchasdisease-causingbacteriaandvirusesandotherinfectiousagentsarerecognizedbythebodysimmunesystemasinvaders.Ournaturaldefensesagainsttheseinfectiousagentsareantibodiesproteinsthatseekouttheantigens抗原andhelpdestroythem. Antibodieshavetwoveryusefulcharacteristics.Firsttheyareextremelyspecific;thatiseachantibodybindstoandattacksoneparticularantigen.Secondsomeantibodiesonceactivatedbytheoccurrenceofadiseasecontinuetoconferresistanceagainstthatdisease.Classicexamplearetheantibodiestothechildhooddiseasesofchickenpox水痘andmeasles. Thesecondcharacteristicofantibodiesmakesitpossibletodevelopvaccines.Avaccine痘苗isapreparationofkilledorweakenedbacteriaorvirusesthatwhenintroducedintothebodystimulatestheproductionofantibodiesagainsttheantigensitcontains. Itisthefirsttraitofantibodiestheirspecificitythatmakesmonoclonalantibodytechnologysovaluable.Notonlycanantibodiesbeusedtherapeutically在治疗上toprotectagainstdisease;theycanalsohelpto.diagnoseawidevarietyofillnessesandcandetectthepresenceofdrugsviralandbacterialproductsandotherunusualorabnormalsubstancesintheblood. Givensuchadiversityofusesforthesediseased-fightingsubstancestheirproductioninpurequantitieshaslongbeenthefocusofscientificinvestigation.Theconventionalmethodwastoinjectalaboratoryanimalwithanantigenandthenafterantibodieshadbeenformedcollectthoseantibodiesfromthebloodserum血清Antibodycontainingbloodserumiscalledantiserum抗血清.Therearetwoproblemswiththismethod:Ityieldsantiserumthatcontainsundesiredsubstancesanditprovidesaverysmallamountofusableantibody. Monoclonalantibodytechnologyallowsustoproducelargeamountsofpureantibodies.inthefollowingway:wecanobtaincellsthatproduceantibodiesnaturally;wealsohaveavailableaclassofcellsthatcangrowcontinuallyincellculture培养.Ifweformahybrid混血儿thatcombinesthecharacteristicofimmortality永生withtheabilitytoproducethedesiredsubstancewewouldhaveineffectafactorytoproduceantibodiesthatworkaroundtheclock. Inmonoclonalantibodytechnologytumorcellsthatcanreplicate重复endlesslyarefusedwithmammaliancellsthatproduceanantibody.Theresultofthiscellfusionisahybridoma杂交瘤whichwillcontinuallyproduceantibodies.Theseantibodiesarecalledmonoclonalbecausetheycomefromonlyonetypeofcellthehybridomacell;antibodiesproducedbyconventionalmethodsontheotherhandarederivedfrompreparationscontainingmanykindsofcellsandhencearecalledpolyclonal.Anexampleofhowmonoclonalantibodiesarederivedisdescribedbelow. Amyelomaisatumorofthebonemarrow骨髓thatcanbeadaptedtogrowpermanendyincellculture.Whenmyelomacellswerefusedwithantibody-producingmammalianspleencellsitwasfoundthattheresultinghybridcellsorhybridomasproducedlargeamountsofmonoclonal骨髓瘤antibody.Thisproductofcellfusioncombinedthedesiredqualitiesofthetwodifferenttypesofcells:theabilitytogrowcontinuallyandtheabilitytoproducelargeamountsofpureantibody. Becauseselectedhybridcellsproduceonlyonespecificantibodytheyaremorepurethanthepolyclonalantibodiesproducedbyconventionaltechniques.Theyarepotentiallymoreeffectivethanconventionaldrugsinfightingdiseasesincedrugsattacknotonlytheforeignsubstancebutthebody’sowncellsaswellsometimesproducingundesirablesideeffectssuchasnausea恶心andallergicreactions.Monoclonalantibodiesattackthetargetmoleculeandonlythetargetmoleculewithnoorgreatlydiminishedsideeffects. Thepolyclonalantibodiesaredifferentfromthemonoclonalonesinallthefollowingwaysexceptthat______.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
Theconstructionoftherailwayissaidtohavebeen{{U}}terminated{{/U}}.
UnitedNations AmajorsegmentoftheUntiedNationsistheGeneralAssemblywhichconsistsofrepresentativesfromallgovernmentsthathaveratifiedtheUNCharter.Asof1995185stateshadmembershipinthegeneralAssembly.AdditionallytheVaticanSwitzerlandandthePalestineLiberationOrganizationhavenonvotingobserverstatusintheGeneralAssembly.TheGeneralAssemblyapprovestheUN’’sbudgetactswiththeSecurityCounciltoselecttheSecretary-generalandjudgesoftheInternationalCourtofJusticeandpassesresolutionsonissuesrangingfromself-determinationandcolonialismtowomen’’srightsandtheglobaldistributionofwealth. TheGeneralAssemblycanmeetandvoteonanysubjectunlesstheSecurityCouncilisdealingwithitoratleastpretendingto.Howeveritsdecisionsonlycarrymoralforce—unliketheCouncil’’s.They’’renotbindingininternationallaws.ButtheAssemblyvotesareanimportantopinionpollonhowandwhatthemajorityoftheworldthinksaboutissues.Importantquestionsneedatwo-thirdsvoteoftheAssemblytopass. Thequestionofwhatisanimportantquestionisn’’timportant.Itsdecidedbythedelegatesthemselves—byasimplemajority. AlthoughtheGeneralAssemblyhasnotrecognizedauthoritytoenforceitsconclusionsonanythingotherthaninternalUNmattersitmakesitsviewpointsonissuesthatarebroughtbeforeitisknowninoneofthethreeways.AGeneralAssemblydeclarationisabroadstatementofgeneralprinciplesuchastheUniversalDeclarationofHumanRightspassedin1948.Declarationsareoftenputforwardasanexpressionofanidealinpracticetheyareregularlyignored.AGeneralAssemblyresolutionisessentiallyadocumentthatrecommendsthatmemberstatestakeaparticularpolicyaction.StatesclaimsovereigntyandmaketheirowndecisionsastowhethertheywillfollowaGeneralAssemblyresolution.Insomecaseshoweverifmanystatesimplementaparticularresolutionotherstatesthatmaynotwishtoactontheresolutionmayfeelthemselvespressuredtodosoanyway.Attheveryleastaresolutionhastheeffectoflegitimizingthepoliciesofthosestatesthatwishtocomplywiththeresolution.FinallyaGeneralAssemblyconventionortreatyhastwomeanings.ThemorecomprehensiveconventionreferstomultilateraltreatiesvotedonbytheGeneralAssemblythatuponpassagebytheGeneralAssemblyarecarriedbacktothecapitalsofmemberstatesforratificationbywhatevermeanseachstateusesdomestically.InothercasesaGeneralAssemblyconventionrefersspecificallytoatreatysignedbetweentheUnitedNationsandthegovernmentofanation-stateaswhenin1956EgyptagreedtoallowUnitedNationspeacekeepingforcestoenterEgyptianterritory. Multi-lateraltreatieshavetoberatifiedbythememberstatebeforeitispassedbytheGeneralAssembly.
Euthanasia:aHeatedlyDebatedTopic Wemustn’’tdelayanylonger...?swallowing吞咽isdifficult...andbreathingthat’’salsodifficult.Thosemusclesareweakeningtoo...wemustn’’tdelayanylonger. ThesewerethewordsofDutchman荷兰人CeesvanwendeldeJoodeaskinghisdoctortohelphimdie.AffectedwithaseriousdiseasevanVendelwasnolongerabletospeakclearlyandheknewtherewasnohopeofrecoveryandthathisconditionwasrapidlydeteriorating. VanVenderslastthreemonthsoflifebeforebeinggivenafinallethalinjectionbyhisdoctorwerefilmedandfirstshownontelevisionlastyearintheNetherlands.Theprogrammehassincebeenboughtby20countriesandeachtimeitisshownitstartsanationwidedebateonthesubject. TheNetherlandsistheonlycountryinEuropewhichpermitseuthanasia安乐死althoughitisnottechnicallylegalthere.HoweverdoctorswhocarryouteuthanasiaunderstrictguidelinesintroducedbytheDutchParliament议会twoyearsagoareusuallynotprosecuted.Theguidelinesdemandthatthepatientisexperiencingextremesufferingthatthereisnochanceofacureandthatthepatienthasmaderepeatedrequestsforeuthanasia.Inadditiontothisaseconddoctormustconfirm证实thatthesecriteriahavebeenmetandthedeathmustbereportedtothepolicedepartment. Shoulddoctorsbeallowedtotaketheliveofothers?Dr.WilfredVanOijenCeesvanVendel’’sdoctorexplainshowhelooksatthequestion: Wellit’’snotasifIinplanningtomurderacrowdofpeoplewithamachinegun.InthatcasekillingistheworstthingIcanimagine.Butthat’’sentirelydifferentfrommyworkasadoctor.IcareforpeopleandItrytoensurethattheydon’tsuffertoomuch.That’’sverydifferentthing. Manypeoplethougharetotallyagainstthepracticeofeuthanasia.Dr.AndrewFergusonChairmanoftheorganizationHealthcareopposedtoEuthanasiasaysthatinthevastmajorityofeuthanasiacaseswhatthepatientisactuallyaskingforissomethingelse.Theymaywantahealthprofessionaltoopenupcommunicationforthemwiththeirlovedonesorfamily—there’’snearlyalwaysanotherquestionbehindthequestion. Britainalsohasastrongtraditionofhospices—specialhospitalswhichcareonlyforthedyingandtheirspecialneeds.CicelySaundersPresidentoftheNationalHospiceCouncilandafoundermemberofthehospicemovementarguesthateuthanasiadoesn’’ttakeintoaccountthattherearewaysofcaringforthedying.Sheisalsoconcernedthatallowingeuthanasiawouldunderminetheneedforcareandconsiderationofawiderangeofpeople;It’’sveryeasyinsocietynowfortheelderlythedisabled伤残的andthedependenttofeelthattheyareburdensandthereforethattheyoughttoopt脱离out.Ithinkthatanythingthatlegallyallowstheshorteningoflifedoesmakethosepeoplemorevulnerable脆弱的. Manyfindthisprohibitionofanindividual’’srighttothepaternalistic家长式的.Althoughtheyagreethatlifeisimportantandshouldberespectedtheyfeelthatthequalityoflifeshouldnotbeignored.Dr.VanOijenbelievesthatpeoplehavethefundamentalrighttochooseforthemselvesiftheywanttodie:Whatthosepeoplewhoopposeeuthanasiaaretellingmeisthatdyingpeoplehaven’ttheright.Andthatwhenpeopleareveryillweareallafraidoftheirdeath.Buttherearesituationswheredeathisafriend.Andinthosecaseswhynot? Butwhynot?isaquestionwhichmightcausestrongemotion.ThefilmshowingCeesVanVendel’’sdeathwasbothmovingandsensitive.Hisdoctorwasclearlyafamilyfriend;hiswifehadonlyherhusband’’sinterestsatheart.Somehoweverwouldarguethatitwouldbedangeroustousethisparticularexampletosupportthecaseforeuthanasia.Notallpatientswouldreceivesuchahighlevelofindividualcareandattention. Dr.WilfredVanOijenmayagreethat______.
OnAntibodies Substancesforeigntothebodysuchasdisease-causingbacteriaandvirusesandotherinfectiousagentsarerecognizedbythebodysimmunesystemasinvaders.Ournaturaldefensesagainsttheseinfectiousagentsareantibodiesproteinsthatseekouttheantigens抗原andhelpdestroythem. Antibodieshavetwoveryusefulcharacteristics.Firsttheyareextremelyspecific;thatiseachantibodybindstoandattacksoneparticularantigen.Secondsomeantibodiesonceactivatedbytheoccurrenceofadiseasecontinuetoconferresistanceagainstthatdisease.Classicexamplearetheantibodiestothechildhooddiseasesofchickenpox水痘andmeasles. Thesecondcharacteristicofantibodiesmakesitpossibletodevelopvaccines.Avaccine痘苗isapreparationofkilledorweakenedbacteriaorvirusesthatwhenintroducedintothebodystimulatestheproductionofantibodiesagainsttheantigensitcontains. Itisthefirsttraitofantibodiestheirspecificitythatmakesmonoclonalantibodytechnologysovaluable.Notonlycanantibodiesbeusedtherapeutically在治疗上toprotectagainstdisease;theycanalsohelpto.diagnoseawidevarietyofillnessesandcandetectthepresenceofdrugsviralandbacterialproductsandotherunusualorabnormalsubstancesintheblood. Givensuchadiversityofusesforthesediseased-fightingsubstancestheirproductioninpurequantitieshaslongbeenthefocusofscientificinvestigation.Theconventionalmethodwastoinjectalaboratoryanimalwithanantigenandthenafterantibodieshadbeenformedcollectthoseantibodiesfromthebloodserum血清Antibodycontainingbloodserumiscalledantiserum抗血清.Therearetwoproblemswiththismethod:Ityieldsantiserumthatcontainsundesiredsubstancesanditprovidesaverysmallamountofusableantibody. Monoclonalantibodytechnologyallowsustoproducelargeamountsofpureantibodies.inthefollowingway:wecanobtaincellsthatproduceantibodiesnaturally;wealsohaveavailableaclassofcellsthatcangrowcontinuallyincellculture培养.Ifweformahybrid混血儿thatcombinesthecharacteristicofimmortality永生withtheabilitytoproducethedesiredsubstancewewouldhaveineffectafactorytoproduceantibodiesthatworkaroundtheclock. Inmonoclonalantibodytechnologytumorcellsthatcanreplicate重复endlesslyarefusedwithmammaliancellsthatproduceanantibody.Theresultofthiscellfusionisahybridoma杂交瘤whichwillcontinuallyproduceantibodies.Theseantibodiesarecalledmonoclonalbecausetheycomefromonlyonetypeofcellthehybridomacell;antibodiesproducedbyconventionalmethodsontheotherhandarederivedfrompreparationscontainingmanykindsofcellsandhencearecalledpolyclonal.Anexampleofhowmonoclonalantibodiesarederivedisdescribedbelow. Amyelomaisatumorofthebonemarrow骨髓thatcanbeadaptedtogrowpermanendyincellculture.Whenmyelomacellswerefusedwithantibody-producingmammalianspleencellsitwasfoundthattheresultinghybridcellsorhybridomasproducedlargeamountsofmonoclonal骨髓瘤antibody.Thisproductofcellfusioncombinedthedesiredqualitiesofthetwodifferenttypesofcells:theabilitytogrowcontinuallyandtheabilitytoproducelargeamountsofpureantibody. Becauseselectedhybridcellsproduceonlyonespecificantibodytheyaremorepurethanthepolyclonalantibodiesproducedbyconventionaltechniques.Theyarepotentiallymoreeffectivethanconventionaldrugsinfightingdiseasesincedrugsattacknotonlytheforeignsubstancebutthebody’sowncellsaswellsometimesproducingundesirablesideeffectssuchasnausea恶心andallergicreactions.Monoclonalantibodiesattackthetargetmoleculeandonlythetargetmoleculewithnoorgreatlydiminishedsideeffects. Allthefollowingstatementsaboutantibodiesaretrueexcept______.
Suburb Ifsuburbismeantanurbanmarginthatgrowsmorerapidlythanitsalreadydevelopedinteriortheprocessofsuburbanizationbeganduringtheemergenceoftheindustrialcityinthesecondquarterofthenineteenthcentury.Beforethatperiodthecitywasasmallhighlycompactclusterinwhichpeoplemovedaboutonfootandgoodswereconveyedbyhorseandcart.Buttheearlyfactoriesbuiltinthe1830’’sand1840’’swerelocatedalongwaterwaysandnearrailheadsattheedgesofcitiesandhousingwasneededforthethousandsofpeopledrawnbytheprospectofemployment.Intimethefactoriesweresurroundedbyproliferatingmilltownsofapartmentsandrowhousesaroundtheoldermaincities.Asadefenceagainstthisencroachmentandtoenlargetheirtaxbasesthecitiesappropriatedtheirindustrialneighbors.In1854forexamplethecityofPhiladelphiaannexedmostofPhiladelphiaCounty.SimilarmunicipalmaneuverstookplaceinChicagoandinNewYork.IndeedmostgreatcitiesoftheUnitedStatesachievedsuchstatusonlybyincorporatingthecommunitiesalongtheirborders. Withtheaccelerationofindustrialgrowthcomeacuteurbancrowdingandaccompanyingsocialstress-conditionsbegantoapproachdisastrousproportionswhenin1888thefirstcommerciallysuccessfulelectrictractionlinewasdeveloped.Withinafewyearsthehorse-drawntrolleyswereretiredandelectricstreetcarnetworkscrisscrossedandconnectedeverymajorurbanareafosteringawaveofsuburbanizationthattransformedthecompactindustrialcityintoadispersedmetropolis.Thisfirstphaseofmass-scalesuburbanizationwasreinforcedbythesimultaneousemergenceoftheurbanmiddleclasswhosedesiresforhomeownershipinneighborhoodsfarfromtheaginginnercityweresatisfiedbythedevelopingofsingle-familyhousingtracts. Itcanbeinferredfromthetextthatafter1890mostpeopletraveledaroundcitiesby______.
Heimpressedallhiscolleaguesasa{{U}}vigorous{{/U}}manintheprimeofhiscareer.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
Suburb Ifsuburbismeantanurbanmarginthatgrowsmorerapidlythanitsalreadydevelopedinteriortheprocessofsuburbanizationbeganduringtheemergenceoftheindustrialcityinthesecondquarterofthenineteenthcentury.Beforethatperiodthecitywasasmallhighlycompactclusterinwhichpeoplemovedaboutonfootandgoodswereconveyedbyhorseandcart.Buttheearlyfactoriesbuiltinthe1830’’sand1840’’swerelocatedalongwaterwaysandnearrailheadsattheedgesofcitiesandhousingwasneededforthethousandsofpeopledrawnbytheprospectofemployment.Intimethefactoriesweresurroundedbyproliferatingmilltownsofapartmentsandrowhousesaroundtheoldermaincities.Asadefenceagainstthisencroachmentandtoenlargetheirtaxbasesthecitiesappropriatedtheirindustrialneighbors.In1854forexamplethecityofPhiladelphiaannexedmostofPhiladelphiaCounty.SimilarmunicipalmaneuverstookplaceinChicagoandinNewYork.IndeedmostgreatcitiesoftheUnitedStatesachievedsuchstatusonlybyincorporatingthecommunitiesalongtheirborders. Withtheaccelerationofindustrialgrowthcomeacuteurbancrowdingandaccompanyingsocialstress-conditionsbegantoapproachdisastrousproportionswhenin1888thefirstcommerciallysuccessfulelectrictractionlinewasdeveloped.Withinafewyearsthehorse-drawntrolleyswereretiredandelectricstreetcarnetworkscrisscrossedandconnectedeverymajorurbanareafosteringawaveofsuburbanizationthattransformedthecompactindustrialcityintoadispersedmetropolis.Thisfirstphaseofmass-scalesuburbanizationwasreinforcedbythesimultaneousemergenceoftheurbanmiddleclasswhosedesiresforhomeownershipinneighborhoodsfarfromtheaginginnercityweresatisfiedbythedevelopingofsingle-familyhousingtracts. Theauthormentionsthatareasborderingthecitieshavegrownduringtheperiodof______.
TheUnitedStates In1782【51】theUnitedStateswonitsindependencethebaldeaglewaschosen【52】thenationalbirdofthenewcountry.Americanleaderswantedtheeagletobea【53】oftheircountrybecauseit’’sabirdofstrengthandcourage.TheychosethebaldeaglebecauseitwasfoundalloverNorthAmericaandonlyinNorthAmerica. Butalittleover200years【54】thebaldeaglehadalmostdisappearedfromthecountryIn1972therewereonly3000baldeaglesintheentireUnitedStates.Thereasonforthebirds【55】populationwaspollutionespeciallypollutionofriversbypesticides.Pesticidesarechemicals【56】tokillinsectsandotheranimalsthatattackanddestroycrops. 【57】rainoftenwashespesticidesintorivers.Pesticidespollutetheriversandpoisonthefish.Eagleseat【58】andthepoison【59】theireggs.Theeggshaveverythinshellsanddonothatch. Eagles【60】onlytwoorthreeeggsayear.Becausemanyoftheeggsdidnot【61】andproducemoreeagles【62】eaglesquickly【63】smaller. TodaytheAmericanGovernmentandtheAmericanpeoplearetryingtoprotectthebaldeagle.Thenumberofbaldeagles【64】Itnowappears【65】theAmericannationalbirdwillsurviveandremainasymbolofstrengthandcourage.
Euthanasia:aHeatedlyDebatedTopic Wemustn’’tdelayanylonger...?swallowing吞咽isdifficult...andbreathingthat’’salsodifficult.Thosemusclesareweakeningtoo...wemustn’’tdelayanylonger. ThesewerethewordsofDutchman荷兰人CeesvanwendeldeJoodeaskinghisdoctortohelphimdie.AffectedwithaseriousdiseasevanVendelwasnolongerabletospeakclearlyandheknewtherewasnohopeofrecoveryandthathisconditionwasrapidlydeteriorating. VanVenderslastthreemonthsoflifebeforebeinggivenafinallethalinjectionbyhisdoctorwerefilmedandfirstshownontelevisionlastyearintheNetherlands.Theprogrammehassincebeenboughtby20countriesandeachtimeitisshownitstartsanationwidedebateonthesubject. TheNetherlandsistheonlycountryinEuropewhichpermitseuthanasia安乐死althoughitisnottechnicallylegalthere.HoweverdoctorswhocarryouteuthanasiaunderstrictguidelinesintroducedbytheDutchParliament议会twoyearsagoareusuallynotprosecuted.Theguidelinesdemandthatthepatientisexperiencingextremesufferingthatthereisnochanceofacureandthatthepatienthasmaderepeatedrequestsforeuthanasia.Inadditiontothisaseconddoctormustconfirm证实thatthesecriteriahavebeenmetandthedeathmustbereportedtothepolicedepartment. Shoulddoctorsbeallowedtotaketheliveofothers?Dr.WilfredVanOijenCeesvanVendel’’sdoctorexplainshowhelooksatthequestion: Wellit’’snotasifIinplanningtomurderacrowdofpeoplewithamachinegun.InthatcasekillingistheworstthingIcanimagine.Butthat’’sentirelydifferentfrommyworkasadoctor.IcareforpeopleandItrytoensurethattheydon’tsuffertoomuch.That’’sverydifferentthing. Manypeoplethougharetotallyagainstthepracticeofeuthanasia.Dr.AndrewFergusonChairmanoftheorganizationHealthcareopposedtoEuthanasiasaysthatinthevastmajorityofeuthanasiacaseswhatthepatientisactuallyaskingforissomethingelse.Theymaywantahealthprofessionaltoopenupcommunicationforthemwiththeirlovedonesorfamily—there’’snearlyalwaysanotherquestionbehindthequestion. Britainalsohasastrongtraditionofhospices—specialhospitalswhichcareonlyforthedyingandtheirspecialneeds.CicelySaundersPresidentoftheNationalHospiceCouncilandafoundermemberofthehospicemovementarguesthateuthanasiadoesn’’ttakeintoaccountthattherearewaysofcaringforthedying.Sheisalsoconcernedthatallowingeuthanasiawouldunderminetheneedforcareandconsiderationofawiderangeofpeople;It’’sveryeasyinsocietynowfortheelderlythedisabled伤残的andthedependenttofeelthattheyareburdensandthereforethattheyoughttoopt脱离out.Ithinkthatanythingthatlegallyallowstheshorteningoflifedoesmakethosepeoplemorevulnerable脆弱的. Manyfindthisprohibitionofanindividual’’srighttothepaternalistic家长式的.Althoughtheyagreethatlifeisimportantandshouldberespectedtheyfeelthatthequalityoflifeshouldnotbeignored.Dr.VanOijenbelievesthatpeoplehavethefundamentalrighttochooseforthemselvesiftheywanttodie:Whatthosepeoplewhoopposeeuthanasiaaretellingmeisthatdyingpeoplehaven’ttheright.Andthatwhenpeopleareveryillweareallafraidoftheirdeath.Buttherearesituationswheredeathisafriend.Andinthosecaseswhynot? Butwhynot?isaquestionwhichmightcausestrongemotion.ThefilmshowingCeesVanVendel’’sdeathwasbothmovingandsensitive.Hisdoctorwasclearlyafamilyfriend;hiswifehadonlyherhusband’’sinterestsatheart.Somehoweverwouldarguethatitwouldbedangeroustousethisparticularexampletosupportthecaseforeuthanasia.Notallpatientswouldreceivesuchahighlevelofindividualcareandattention. WhentheauthorsaysButwhynot?isaquestionmightcausestrongemotionthelastpara.hemaymean______.
UnitedNations AmajorsegmentoftheUntiedNationsistheGeneralAssemblywhichconsistsofrepresentativesfromallgovernmentsthathaveratifiedtheUNCharter.Asof1995185stateshadmembershipinthegeneralAssembly.AdditionallytheVaticanSwitzerlandandthePalestineLiberationOrganizationhavenonvotingobserverstatusintheGeneralAssembly.TheGeneralAssemblyapprovestheUN’’sbudgetactswiththeSecurityCounciltoselecttheSecretary-generalandjudgesoftheInternationalCourtofJusticeandpassesresolutionsonissuesrangingfromself-determinationandcolonialismtowomen’’srightsandtheglobaldistributionofwealth. TheGeneralAssemblycanmeetandvoteonanysubjectunlesstheSecurityCouncilisdealingwithitoratleastpretendingto.Howeveritsdecisionsonlycarrymoralforce—unliketheCouncil’’s.They’’renotbindingininternationallaws.ButtheAssemblyvotesareanimportantopinionpollonhowandwhatthemajorityoftheworldthinksaboutissues.Importantquestionsneedatwo-thirdsvoteoftheAssemblytopass. Thequestionofwhatisanimportantquestionisn’’timportant.Itsdecidedbythedelegatesthemselves—byasimplemajority. AlthoughtheGeneralAssemblyhasnotrecognizedauthoritytoenforceitsconclusionsonanythingotherthaninternalUNmattersitmakesitsviewpointsonissuesthatarebroughtbeforeitisknowninoneofthethreeways.AGeneralAssemblydeclarationisabroadstatementofgeneralprinciplesuchastheUniversalDeclarationofHumanRightspassedin1948.Declarationsareoftenputforwardasanexpressionofanidealinpracticetheyareregularlyignored.AGeneralAssemblyresolutionisessentiallyadocumentthatrecommendsthatmemberstatestakeaparticularpolicyaction.StatesclaimsovereigntyandmaketheirowndecisionsastowhethertheywillfollowaGeneralAssemblyresolution.Insomecaseshoweverifmanystatesimplementaparticularresolutionotherstatesthatmaynotwishtoactontheresolutionmayfeelthemselvespressuredtodosoanyway.Attheveryleastaresolutionhastheeffectoflegitimizingthepoliciesofthosestatesthatwishtocomplywiththeresolution.FinallyaGeneralAssemblyconventionortreatyhastwomeanings.ThemorecomprehensiveconventionreferstomultilateraltreatiesvotedonbytheGeneralAssemblythatuponpassagebytheGeneralAssemblyarecarriedbacktothecapitalsofmemberstatesforratificationbywhatevermeanseachstateusesdomestically.InothercasesaGeneralAssemblyconventionrefersspecificallytoatreatysignedbetweentheUnitedNationsandthegovernmentofanation-stateaswhenin1956EgyptagreedtoallowUnitedNationspeacekeepingforcestoenterEgyptianterritory. TheGeneralAssemblyhavetheauthoritytoenforceitsconclusionsonapprovingUNbudget.
Thebossputgreatstressontheworkerssothattheycouldworkharder.
Thenewjobwillprovideyouwith{{U}}invaluable{{/U}}experience.
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