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greatly speeded the development of medicine brought no immediate progress in the research of gene-therapy promised a cure to every disease made him a national hero
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A team at the California-based Salk Institute, one of the world’s leading research centers on biological sciences, has created a special new breed of HIV and has started negotiations with the US Food and Drug Administration (FD to begin clinical gene therapy (治疗) trials this year. The first trials are expected to involve patients suffering from cancers that cannot be cured by surgery although project leader Professor Inder Verma said the HIV technique would have "far wider applications". The plan remains very likely to cause controversy since it involves making use of a virus which has caused more than 22 million deaths around the world in the past two decades. Verma said that the idea of using HIV for a beneficial purpose was "shocking" but the fierce nature of HIV had disappeared by having all six of the potentially deadly genes removed. Illnesses such as various cancers are caused when a gene in a patient’s body fails to work properly. In the past two years, breakthroughs in genetics (遗传学) have led gene therapy scientists to try and replace the genes that do not function normally. Unfortunately, the body’s immune defenses have been known to attack the modified genes and make them lose their effects before they can start their task and progress in the field has been held up by the lack of a suitable carrier. The HIV virus has the ability to escape from, and then destroy, the immune defense ceils designed to protect our bodies and this makes it attractive to scientists as a way of secretly conveying replacement genes into patients’ bodies.
show the promise of gene-therapy give an example of modem treatment for fatal diseases introduce the achievement of Anderson and his team explain how gene-based treatment works
Ashanthi needs to receive gene-therapy treatment constantly. Despite the huge funding, gene researches have shown few promises. Therapeutic genes are carried by harmless viruses. Gene-doping is encouraged by world agencies to help athletes get better scores.
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