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Directions: Supposeyouareacollegestudentonaschoolcampusoranemployeeinacompany.Recentlyyounoticedthatsomepeopleneverpaidattentiontothesignsonagarbagecanthatsayitisdesirabletodealwithwastesseparately.Nowyouaregoingtomakeaconservationcampaignspeechataparty.Andyourspeechshouldinclude: 1thepresentsituation 2andyoursuggestions. Writeyourletterinnolessthan100words.WriteitneatlyonANSWERSHEET2. Donotsignyourownnameattheendoftheletteruse"LiMing"instead. Donotwritetheaddress.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire. Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Directions: ReadthefollowingtextcarefullyandthentranslatetheunderlinedsegmentsintoChinese.YourtranslationshouldbewrittenneatlyonANSWERSHEET2. ThelongandprogressivereignofQueenVictoriacametoaclimaxatatimeofpeaceandplentywhentheBritishEmpireseemedtobeatthesummitofitspowerandsecurity.OfthediscordthatsoonfollowedweshallherenoteonlytwofactorswhichhadlargeinfluenceoncontemporaryEnglishliterature. ThefirstdisturbingfactorwasimperialismthereawakeningofadominatingspiritwhichhadseeminglybeenputtosleepbytheproclamationofanImperialFederation.46ItscomingwasheraldedbytheBoerWarinSouthAfricathroughwhichBritainblunderedtowhatwashopedtobeaneraofpeaceandgoodwill.Othernationspromptlymadesuchhopeavainwhistlinginthewind.JapaneseWarLordsbeganacareerofconquestwhichaimedtomakeJapanmasterofAsiaandEastIndies.Pacificislandsthathadforagessleptpeacefullywereturnedintofrowningnavalstations.47EventheUnitedStatesarousedbyaneasytriumphintheSpanishWarstartedonanimperialisticadventurebytaking’controlofthePhilippinesthusmakinganimplacableenemyofJapan. Onlyanationthatentersonadangerouscoursewitheyeswideopenhasanychanceofasafewayoutandtheimperialisticnationswereallalikeblind.48AninevitableresultwastheFirstWarandthegreathorrorofaSecondWorldWarthetwodisastersbeingdifferentactsofthesametragedyofimperialismseparatedonlybyabreathingspell. Anotherfactorthatinfluencedliteraturefortheworsewasawidespreaddemandforsocialreformofeverykind;notslowandorderlyreformwhichisprogressbutimmediateanduncontrolledreformwhichbreedsaspiritofrebellionanddespair.BeforetheVictorianagehadcometoanendEnglishliteratureappearedtohavelosttouchwithhealthyEnglishlife.ManywritersechoedthesorrowfulcryofJamesThomsoninhisCityofDreadfulNightorbabbledof"artforart’ssake"withOscarWilde.49GroominhissurveyoftheperiodnotesthatwritershadmostlyacriticalattitudetowardmoralsandreligionChurchandStateasrelicsfrom"thedeadhandoftraditionalbeliefs."50SmallwonderthatGermanandJapanesewar-advocatesregardedEnglishmenasadecadentracewhenthesameoraworseopinionwasdailyreadinthenovelsofSamuelButlerandnightlyheardintheplaysofBernardShaw. GroominhissurveyoftheperiodnotesthatwritershadmostlyacriticalattitudetowardmoralsandreligionChurchandStateasrelicsfromthedeadhandoftraditionalbeliefs.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Directions: Thefollowingparagraphsaregiveninawrongorder.ForQuestions41-45youarerequiredtoreorganizetheseparagraphsintoacoherenttextbychoosingfromthelistA-Gtofillineachnumberedbox.ThefirstandthelastparagraphshavebeenplacedforyouinBoxes.MarkyouranswersonANSWERSHEET1.[ A]ThestrainofHIVthatwasdiscoveredinSydneyintriguesscientistsbecauseitcontainsstrikingabnormalitiesinagenethatisbelievedtostimulateviralduplication.Infactthevirusismissingsomuchofthisparticulargene-knownasneffornegativefactor--thatitishardtoimaginehowthegenecouldperformanyusefulfunction.AndsureenoughwhiletheSydneyvirusretainstheabilitytoinfectTcells--whitebloodcellsthatarecriticaltotheimmunesystem’sabilitytowardoffinfection--itmakessofewcopiesofitselfthatthemostpowerfulmoleculartoolscanbarelydetectitspresence. [B]Ifthisspeculationprovesrightitwillmarkamilestoneinthebattletocontainthelate-20thcentury’smostterribleepidemic.ForinadditiontoexplainingwhythissmallgroupofpeopleinfectedwithHIVhasnotbecomesickthediscoveryofaviralstrainthatworkslikeavaccinewouldhavefar-reachingimplications."Whattheseresultssuggest"saysDr.BarneyGrahamofTennessee’sVanderbiltUniversity"isthatHIVisvulnerableandthatitispossibletostimulateeffectiveimmunityagainstit." [C]Butassixyearsstretchedto10thento14theanxietyofhealthofficialsgavewaytoastonishment.Althoughtwooftherecipientshavediedfromothercausesnotoneoftheman’scontaminatedbloodhascomedownwithAIDS.Moretellingstillthedonorisalsohealthy.InfacthisimmunesystemremainsasrobustasifhehadnevertangledwithHIVatall.Whatcouldexplainsuchunexpectedgoodfortune [D]Attheveryleastthenefgeneoffersanattractivetargetfordrugdevelopers.IfitsactivitycanbeblockedsuggestsDeaconresearchersmightbeabletobringtheprogressionofdiseaseundercontroleveninpeoplewhohavedevelopedfull-blownAIDS.TheneedforbetterAIDS-fightingdrugswasunderscoredlastweekbytheactionsofaU.S.FoodandDrugAdministrationadvisorypanelwhichrecommendedspeedyapprovaloftwonewAIDSdrugs.AlthoughFDAcommissionerDavidKesslerwasquicktopraisethenewdrugsneithermedicationcanpreventorcureAIDSonceithastakenhold.Whatscientistsreallywantisavaccinethatcanpreventinfectionaltogether.Andthat’swhatmakestheSydneyvirussopromising--andsocontroversial. [E]AteamofAustralianscientistshasfinallysolvedthemystery.ThevirusthatthedonorcontractedandthenpassedontheteamreportedlastweekinthejournalSciencecontainsflawsinitsgeneticscriptthatappeartohaverendereditharmless."Notonlyhavetherecipientsandthedonornotprogressedtodiseasefor15years"marvelsmolecularbiologistNicholasDeaconofAustralia’sMacfarlaneBurnetCentreforMedicalResearch"butthepredictionisthattheyneverwill."Deaconspeculatesthatthis"impotent"HIVmayevenbeanaturalinoculantthatprotectsitscarriersagainstmorevirulentstrainsofthevirus. [F]ButfewscientistsareenthusiasticabouttestingthepropositionbyinjectingHIV--howeverweakened--intomillionsofpeoplewhohaveneverbeeninfected.AfteralltheynoteHIVisaretrovirusaclassofinfectiousagentsknownfortheiralarmingabilitytointegratetheirowngenesintotheDNAofthecellstheyinfect.Thusonceittakeseffectaretrovirusinfectionispermanent. [G]About15yearsagoawell-meaningmandonatedbloodtotheRedCrossinSydneyAustralianotknowinghehasbeenexposedtoHIV-1thevirusthatcausesAIDS.Muchlaterpublichealthofficialslearnedthatsomeofthepeoplewhogottransfusionscontaininghisbloodhadbecomeinfectedwiththesamevirus;presumablytheywerealmostsuretodie. Order: 45
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Directions: ReadthefollowingtextcarefullyandthentranslatetheunderlinedsegmentsintoChinese.YourtranslationshouldbewrittenneatlyonANSWERSHEET2. ThelongandprogressivereignofQueenVictoriacametoaclimaxatatimeofpeaceandplentywhentheBritishEmpireseemedtobeatthesummitofitspowerandsecurity.OfthediscordthatsoonfollowedweshallherenoteonlytwofactorswhichhadlargeinfluenceoncontemporaryEnglishliterature. ThefirstdisturbingfactorwasimperialismthereawakeningofadominatingspiritwhichhadseeminglybeenputtosleepbytheproclamationofanImperialFederation.46ItscomingwasheraldedbytheBoerWarinSouthAfricathroughwhichBritainblunderedtowhatwashopedtobeaneraofpeaceandgoodwill.Othernationspromptlymadesuchhopeavainwhistlinginthewind.JapaneseWarLordsbeganacareerofconquestwhichaimedtomakeJapanmasterofAsiaandEastIndies.Pacificislandsthathadforagessleptpeacefullywereturnedintofrowningnavalstations.47EventheUnitedStatesarousedbyaneasytriumphintheSpanishWarstartedonanimperialisticadventurebytaking’controlofthePhilippinesthusmakinganimplacableenemyofJapan. Onlyanationthatentersonadangerouscoursewitheyeswideopenhasanychanceofasafewayoutandtheimperialisticnationswereallalikeblind.48AninevitableresultwastheFirstWarandthegreathorrorofaSecondWorldWarthetwodisastersbeingdifferentactsofthesametragedyofimperialismseparatedonlybyabreathingspell. Anotherfactorthatinfluencedliteraturefortheworsewasawidespreaddemandforsocialreformofeverykind;notslowandorderlyreformwhichisprogressbutimmediateanduncontrolledreformwhichbreedsaspiritofrebellionanddespair.BeforetheVictorianagehadcometoanendEnglishliteratureappearedtohavelosttouchwithhealthyEnglishlife.ManywritersechoedthesorrowfulcryofJamesThomsoninhisCityofDreadfulNightorbabbledof"artforart’ssake"withOscarWilde.49GroominhissurveyoftheperiodnotesthatwritershadmostlyacriticalattitudetowardmoralsandreligionChurchandStateasrelicsfrom"thedeadhandoftraditionalbeliefs."50SmallwonderthatGermanandJapanesewar-advocatesregardedEnglishmenasadecadentracewhenthesameoraworseopinionwasdailyreadinthenovelsofSamuelButlerandnightlyheardintheplaysofBernardShaw. EventheUnitedStatesarousedbyaneasytriumphintheSpanishWarstartedonanimperialisticadventurebytaking’controlofthePhilippinesthusmakinganimplacableenemyofJapan.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Directions: Thefollowingparagraphsaregiveninawrongorder.ForQuestions41-45youarerequiredtoreorganizetheseparagraphsintoacoherenttextbychoosingfromthelistA-Gtofillineachnumberedbox.ThefirstandthelastparagraphshavebeenplacedforyouinBoxes.MarkyouranswersonANSWERSHEET1.[ A]ThestrainofHIVthatwasdiscoveredinSydneyintriguesscientistsbecauseitcontainsstrikingabnormalitiesinagenethatisbelievedtostimulateviralduplication.Infactthevirusismissingsomuchofthisparticulargene-knownasneffornegativefactor--thatitishardtoimaginehowthegenecouldperformanyusefulfunction.AndsureenoughwhiletheSydneyvirusretainstheabilitytoinfectTcells--whitebloodcellsthatarecriticaltotheimmunesystem’sabilitytowardoffinfection--itmakessofewcopiesofitselfthatthemostpowerfulmoleculartoolscanbarelydetectitspresence. [B]Ifthisspeculationprovesrightitwillmarkamilestoneinthebattletocontainthelate-20thcentury’smostterribleepidemic.ForinadditiontoexplainingwhythissmallgroupofpeopleinfectedwithHIVhasnotbecomesickthediscoveryofaviralstrainthatworkslikeavaccinewouldhavefar-reachingimplications."Whattheseresultssuggest"saysDr.BarneyGrahamofTennessee’sVanderbiltUniversity"isthatHIVisvulnerableandthatitispossibletostimulateeffectiveimmunityagainstit." [C]Butassixyearsstretchedto10thento14theanxietyofhealthofficialsgavewaytoastonishment.Althoughtwooftherecipientshavediedfromothercausesnotoneoftheman’scontaminatedbloodhascomedownwithAIDS.Moretellingstillthedonorisalsohealthy.InfacthisimmunesystemremainsasrobustasifhehadnevertangledwithHIVatall.Whatcouldexplainsuchunexpectedgoodfortune [D]Attheveryleastthenefgeneoffersanattractivetargetfordrugdevelopers.IfitsactivitycanbeblockedsuggestsDeaconresearchersmightbeabletobringtheprogressionofdiseaseundercontroleveninpeoplewhohavedevelopedfull-blownAIDS.TheneedforbetterAIDS-fightingdrugswasunderscoredlastweekbytheactionsofaU.S.FoodandDrugAdministrationadvisorypanelwhichrecommendedspeedyapprovaloftwonewAIDSdrugs.AlthoughFDAcommissionerDavidKesslerwasquicktopraisethenewdrugsneithermedicationcanpreventorcureAIDSonceithastakenhold.Whatscientistsreallywantisavaccinethatcanpreventinfectionaltogether.Andthat’swhatmakestheSydneyvirussopromising--andsocontroversial. [E]AteamofAustralianscientistshasfinallysolvedthemystery.ThevirusthatthedonorcontractedandthenpassedontheteamreportedlastweekinthejournalSciencecontainsflawsinitsgeneticscriptthatappeartohaverendereditharmless."Notonlyhavetherecipientsandthedonornotprogressedtodiseasefor15years"marvelsmolecularbiologistNicholasDeaconofAustralia’sMacfarlaneBurnetCentreforMedicalResearch"butthepredictionisthattheyneverwill."Deaconspeculatesthatthis"impotent"HIVmayevenbeanaturalinoculantthatprotectsitscarriersagainstmorevirulentstrainsofthevirus. [F]ButfewscientistsareenthusiasticabouttestingthepropositionbyinjectingHIV--howeverweakened--intomillionsofpeoplewhohaveneverbeeninfected.AfteralltheynoteHIVisaretrovirusaclassofinfectiousagentsknownfortheiralarmingabilitytointegratetheirowngenesintotheDNAofthecellstheyinfect.Thusonceittakeseffectaretrovirusinfectionispermanent. [G]About15yearsagoawell-meaningmandonatedbloodtotheRedCrossinSydneyAustralianotknowinghehasbeenexposedtoHIV-1thevirusthatcausesAIDS.Muchlaterpublichealthofficialslearnedthatsomeofthepeoplewhogottransfusionscontaininghisbloodhadbecomeinfectedwiththesamevirus;presumablytheywerealmostsuretodie. Order: 43
Directions: Thefollowingparagraphsaregiveninawrongorder.ForQuestions41-45youarerequiredtoreorganizetheseparagraphsintoacoherenttextbychoosingfromthelistA-Gtofillineachnumberedbox.ThefirstandthelastparagraphshavebeenplacedforyouinBoxes.MarkyouranswersonANSWERSHEET1.[ A]ThestrainofHIVthatwasdiscoveredinSydneyintriguesscientistsbecauseitcontainsstrikingabnormalitiesinagenethatisbelievedtostimulateviralduplication.Infactthevirusismissingsomuchofthisparticulargene-knownasneffornegativefactor--thatitishardtoimaginehowthegenecouldperformanyusefulfunction.AndsureenoughwhiletheSydneyvirusretainstheabilitytoinfectTcells--whitebloodcellsthatarecriticaltotheimmunesystem’sabilitytowardoffinfection--itmakessofewcopiesofitselfthatthemostpowerfulmoleculartoolscanbarelydetectitspresence. [B]Ifthisspeculationprovesrightitwillmarkamilestoneinthebattletocontainthelate-20thcentury’smostterribleepidemic.ForinadditiontoexplainingwhythissmallgroupofpeopleinfectedwithHIVhasnotbecomesickthediscoveryofaviralstrainthatworkslikeavaccinewouldhavefar-reachingimplications."Whattheseresultssuggest"saysDr.BarneyGrahamofTennessee’sVanderbiltUniversity"isthatHIVisvulnerableandthatitispossibletostimulateeffectiveimmunityagainstit." [C]Butassixyearsstretchedto10thento14theanxietyofhealthofficialsgavewaytoastonishment.Althoughtwooftherecipientshavediedfromothercausesnotoneoftheman’scontaminatedbloodhascomedownwithAIDS.Moretellingstillthedonorisalsohealthy.InfacthisimmunesystemremainsasrobustasifhehadnevertangledwithHIVatall.Whatcouldexplainsuchunexpectedgoodfortune [D]Attheveryleastthenefgeneoffersanattractivetargetfordrugdevelopers.IfitsactivitycanbeblockedsuggestsDeaconresearchersmightbeabletobringtheprogressionofdiseaseundercontroleveninpeoplewhohavedevelopedfull-blownAIDS.TheneedforbetterAIDS-fightingdrugswasunderscoredlastweekbytheactionsofaU.S.FoodandDrugAdministrationadvisorypanelwhichrecommendedspeedyapprovaloftwonewAIDSdrugs.AlthoughFDAcommissionerDavidKesslerwasquicktopraisethenewdrugsneithermedicationcanpreventorcureAIDSonceithastakenhold.Whatscientistsreallywantisavaccinethatcanpreventinfectionaltogether.Andthat’swhatmakestheSydneyvirussopromising--andsocontroversial. [E]AteamofAustralianscientistshasfinallysolvedthemystery.ThevirusthatthedonorcontractedandthenpassedontheteamreportedlastweekinthejournalSciencecontainsflawsinitsgeneticscriptthatappeartohaverendereditharmless."Notonlyhavetherecipientsandthedonornotprogressedtodiseasefor15years"marvelsmolecularbiologistNicholasDeaconofAustralia’sMacfarlaneBurnetCentreforMedicalResearch"butthepredictionisthattheyneverwill."Deaconspeculatesthatthis"impotent"HIVmayevenbeanaturalinoculantthatprotectsitscarriersagainstmorevirulentstrainsofthevirus. [F]ButfewscientistsareenthusiasticabouttestingthepropositionbyinjectingHIV--howeverweakened--intomillionsofpeoplewhohaveneverbeeninfected.AfteralltheynoteHIVisaretrovirusaclassofinfectiousagentsknownfortheiralarmingabilitytointegratetheirowngenesintotheDNAofthecellstheyinfect.Thusonceittakeseffectaretrovirusinfectionispermanent. [G]About15yearsagoawell-meaningmandonatedbloodtotheRedCrossinSydneyAustralianotknowinghehasbeenexposedtoHIV-1thevirusthatcausesAIDS.Muchlaterpublichealthofficialslearnedthatsomeofthepeoplewhogottransfusionscontaininghisbloodhadbecomeinfectedwiththesamevirus;presumablytheywerealmostsuretodie. Order: 41
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
Thehumannoseisanunderratedtool.Humansareoftenthoughttobeinsensitivesmellerscomparedwithanimals________thisislargelybecause________animalswestandupright.Thismeansthatournosesare________toperceivingthosesmellswhichfloatthroughtheair________themajorityofsmellswhichsticktosurfaces.Infact________weareextremelysensitivetosmells________wedonotgenerallyrealizeit.Ournosesarecapableof________humansmellsevenwhentheseare________tofarbelowonepartinonemillion. Strangelysomepeoplefindthattheycansmellonetypeofflowerbutnotanother________othersaresensitivetothesmellsofbothflowers.Thismaybebecausesomepeopledonothavethegenesnecessarytogenerate________smellreceptorsinthenose.Thesereceptorsarethecellswhichsensesmellsandsend________tothebrain.Howeverithasbeenfoundthatevenpeopleinsensitivetoacertainsmell________cansuddenlybecomesensitivetoitwhen________toitoftenenough. Theexplanationforinsensitivitytosmellseemstobethatthebrainfindsit________tokeepallsmellreceptorsworkingallthetimebutcan________newreceptorsifnecessary.Thismay________explainwhywearenotusuallysensitivetoourownsmells―wesimplydonotneedtobe.Wearenot________oftheusualsmellofourownhousebutwe________newsmellswhenwevisitsomeoneelse’’s.Thebrainfindsitbesttokeepsmellreceptors________forunfamiliarandemergencysignals________thesmellofsmokewhichmightindicatethedangeroffire.
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